WORLD RECORD FOR CHIMPANZEE TEST TRIAL

When the treatment was used for those with beta thalassemia, 39 of the 42 trial participants did not need to have a red blood cell transfusion for at least 12 months after receiving Casgevy.ĭr Sara Trompeter, a consultant haematologist at University College hospital London and expert in sickle cell disease, said: “Whilst curative treatments may not be suitable for all, gene therapy offers a real chance of cure for those who are not eligible for bone marrow transplants and so we are delighted that it has been approved by MHRA. In a clinical trial of Casgevy for sickle cell disease, 28 of the 29 patients experienced no episodes of major pain – which can lead to them being hospitalised – for at least a year afterwards. The MHRA said patients may need to spend at least a month in hospital while the treated cells “take up residence in the bone marrow and start to make red blood cells with the stable form of haemoglobin”. Welcome to our Chimpanzee Quiz This is the ultimate test of your knowledge about our closest living relatives in the animal kingdom With this quiz, you’ll have the chance to. The chimpanzee (/ t m p æ n z i / Pan troglodytes), also known as simply the chimp, is a species of great ape native to the forest and savannah of tropical Africa.It has four confirmed subspecies and a fifth proposed one. Between 95 and 98 percent of chimpanzees’ DNA is similar to that of humans. To do this, stem cells are taken out of bone marrow, edited in a laboratory and then infused back into the patient, after which the results have the potential to be lifelong.”ĭuring that process, laboratory staff use the “genetic scissors” to edit, or cut, the DNA of the cells from the patient’s bone marrow, before the treated cells are put back through infusion. Chimpanzees can survive 40 to 50 years in the wild and 50 to 60 years in captivity. The MHRA said: “Casgevy is designed to work by editing the faulty gene in a patient’s bone marrow stem cells so that the body produces functioning haemoglobin.

Sickle cell disease and beta thalassemia are genetic, or inherited, conditions caused by errors in the genes for haemoglobin, a protein that lets red blood cells transport oxygen around the body. The charity added that the approval of Casgevy, made by Vertex Pharmaceuticals, was “empowering the NHS to employ it as a groundbreaking therapeutic intervention for those grappling with this condition, marked by chronic anaemia, recurrent episodes of intense pain requiring hospitalisation, organ damage, an elevated risk of stroke and premature mortality”. The Sickle Cell Society welcomed the MHRA’s decision as a “historic moment for the sickle cell community” which “offers newfound hope and optimism”. In honor of humankinds closest living relative, World Chimpanzee Day is a celebration of chimpanzees and an opportunity to raise awareness about the vital need. Until now this has been the only treatment available, even though the body can reject the donor marrow. About 1,000 – mainly of Mediterranean, south Asian, south-east Asian and Middle Eastern background – have beta thalassemia and need regular blood transfusions to treat their anaemia.Įxperts in the illnesses hope Casgevy may be a cure, making it no longer necessary for people with the conditions to have a bone marrow transplant. My question would be, why am I so good at one aspect yet horrendous at another?Īnd how much can I improve? (Raw memory.It is the first medicine licensed anywhere that works by deploying gene editing that uses the “genetic scissors”, known as CRISPR, for which its inventors won the Nobel prize for chemistry.Ĭasgevy’s developers hope the pioneering treatment could banish the pain, infections and anaemia sickle cell disease brings and the severe anaemia experienced by those with beta thalassemia.Ībout 15,000 people in the UK, almost all of African or Caribbean heritage, have sickle cell disease. I usually score in the 20s on the Chimp quiz before I get tired and lose on purpose the same goes with the sequence quiz, only that I end up giving up at the 40 mark (Both in the top percentile).īut I've seen in this sub, people claiming to reach 200-500 in the verbal memory quiz (They also did mention that they struggled with the sequence quiz, making them polar opposites of mine), yet I got 45 twice and then got to 100 when I started to simply repeat the word twice in my head before moving to the next word. I've noticed that I can't determine my limit on Tests like the 'Chimp Test' or 'Sequence Memory' because I simply lose when I get tired. Just wondering how much can you train to get better on these? (I know this has been posted here before) I was just wondering, I started testing my memory using this website:

World record for chimpanzee test